物质信息
ID:181444
名称和标识
IUPAC传统名
3-{2-[2-(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-amino-3-hydroxypropanamido)-4-methylpentanamido]-5-carbamimidamidopentanamido}-5-carbamimidamidopentanamido)-3-hydroxypropanamido]-3-hydroxypropanamido}-3-sulfanylpropanamido)-3-phenylpropanamido]acetamido}acetamido)-5-carbamimidamidopentanamido]-4-(methylsulfanyl)butanamido}-3-({4-carbamimidamido-1-[(1-{[({1-[(1-{[1-({[(1-{[({1-[(1-{[1-({1-[(4-carbamimidamido-1-{[1-carboxy-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl)carbamoyl]-2-phenylethyl}carbamoyl)-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl)carbamoyl]-2-sulfanylethyl}carbamoyl)methyl]carbamoyl}-3-methylbutyl)carbamoyl]methyl}carbamoyl)-2-hydroxyethyl]carbamoyl}-3-carbamoylpropyl)carbamoyl]ethyl}carbamoyl)methyl]carbamoyl}-2-methylbutyl)carbamoyl]butyl}carbamoyl)propanoic acid
IUPAC标准名
3-{2-[2-(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-amino-3-hydroxypropanamido)-4-methylpentanamido]-5-carbamimidamidopentanamido}-5-carbamimidamidopentanamido)-3-hydroxypropanamido]-3-hydroxypropanamido}-3-sulfanylpropanamido)-3-phenylpropanamido]acetamido}acetamido)-5-carbamimidamidopentanamido]-4-(methylsulfanyl)butanamido}-3-({4-carbamimidamido-1-[(1-{[({1-[(1-{[1-({[(1-{[({1-[(1-{[1-({1-[(4-carbamimidamido-1-{[1-carboxy-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl)carbamoyl]-2-phenylethyl}carbamoyl)-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl)carbamoyl]-2-sulfanylethyl}carbamoyl)methyl]carbamoyl}-3-methylbutyl)carbamoyl]methyl}carbamoyl)-2-hydroxyethyl]carbamoyl}-3-carbamoylpropyl)carbamoyl]ethyl}carbamoyl)methyl]carbamoyl}-2-methylbutyl)carbamoyl]butyl}carbamoyl)propanoic acid
别名
Atrial Natriuretic Peptide humanANF 1-28hANF
化合物性质
安全信息
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
保存温度
-20°C
德国WGK号
3
药理学性质
相关基因信息
human ... NPPA(4878)
产品相关信息
纯度
≥97% (HPLC)
描述信息
Amino Acid Sequence
Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr [Disulfide bridge: 7-23]
Biochem/physiol Actions
Atrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. It exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure homeostasis.
Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr [Disulfide bridge: 7-23]
Biochem/physiol Actions
Atrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. It exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure homeostasis.
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