物质信息
ID:181327
名称和标识
别名
α-D-GalNAc-1→OCH2PhBenzyl 2-acetamido-2-deoxy-α-D-galactopyranosideGalNAc α-O-benzylBenzyl N-acetyl-α-D-galactosaminideBenzyl-α-GalNAcGalNAc-O-bn
IUPAC标准名
N-[2-(benzyloxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
IUPAC传统名
N-[2-(benzyloxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
化合物性质
安全信息
保存温度
-20°C
德国WGK号
3
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
描述信息
Application
Benzyl 2-acetamido-2-deoxy-α-D-galactopyranoside (BADGP), an O-GlcNAc (OGT) transferase inhibitor, is used to study the physiological effects of O-glycosylation modulation.
Biochem/physiol Actions
Benzyl-N-acetyl-α-galactosaminide inhibits glycosyltransferase incorporation of glucosamine into O-glycans. Suppresses mucin biosynthesis1,2 and inhibits MUC1 expression in breast cancer cell line MDF-7.3
Benzyl 2-acetamido-2-deoxy-α-D-galactopyranoside (BADGP), an O-GlcNAc (OGT) transferase inhibitor, is used to study the physiological effects of O-glycosylation modulation.
Biochem/physiol Actions
Benzyl-N-acetyl-α-galactosaminide inhibits glycosyltransferase incorporation of glucosamine into O-glycans. Suppresses mucin biosynthesis1,2 and inhibits MUC1 expression in breast cancer cell line MDF-7.3
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