物质信息
ID:181233
名称和标识
别名
Tropisetron monohydrochloride3-Tropanylindole-3-carboxylate monohydrochlorideICS-205,930Navobanendo-8-Methyl-8-azabicyclo[3.2.1]oct-3-ol Indol-3-yl-carboxylate 盐酸盐Tropisetron
IUPAC标准名
8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride
IUPAC传统名
8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate hydrochloride
化合物性质
理化性质
溶解度
H2O: >10 mg/mL
外观
solid
安全信息
德国WGK号
3
保存温度
2-8°C
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
药理学性质
相关基因信息
human ... CHRNA3(1136), CHRNA4(1137), CHRNB2(1141), CHRNB4(1143), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242)rat ... Chrna7(25302), Drd2(24318), Htr1a(24473), Htr3a(79246)
产品相关信息
纯度
≥98% (HPLC)
描述信息
Biochem/physiol Actions
3-Tropanylindole-3-carboxylate hydrochloride is a selective 5-HT3 serotonin receptor antagonist.
Tropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment.
3-Tropanylindole-3-carboxylate hydrochloride is a selective 5-HT3 serotonin receptor antagonist.
Tropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment.
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