物质信息

ID:180991

多西环素 单盐酸半乙醇半水合物

名称和标识
IUPAC标准名
bis((4S,5S,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide) ethanol hydrate dihydrochloride
IUPAC传统名
bis((4S,5S,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide) ethyl alcohol hydrate dihydrochloride
别名
多西环素盐酸盐半乙醇化物半水合物Doxycycline hyclate多西环素 单盐酸半乙醇半水合物
数据登录号
Beilstein号
PubChem SID
化合物性质
安全信息
保存温度
2-8°C
GHS危险品标识
GHS07
急性毒性(口服,皮肤接触,吸入),类别4
皮肤刺激,类别2
眼刺激,类别2
皮肤过敏,类别1
特定目标器官毒性 -一次接触,类别3
GHS警示词
Warning
个人保护装置
dust mask type N95 (US), Eyeshields, Gloves
RTECS编号
QI8925000
GHS危险声明
H302-H315-H319-H335
欧盟危险性物质标志
有害性 有害性 (Xn)
危险公开号
22-36/37/38
安全公开号
26
GHS警示性声明
P261-P305+P351+P338
德国WGK号
3
产品相关信息
纯度
≥98% (TLC)
理化性质
溶解度
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描述信息
Frequently Asked Questions
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Application
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Doxycycline hyclate is a synthetic oxytetracycline derivative. It has been used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and to eliminate Ixodes scapularis ticks1. It is used to inhibit matrix metalloproteinases2 and has been used to inhibit the inflammatory response of Lyme Disease3.
Biochem/physiol Actions
Derivative of oxytetracycline. A broad spectrum inhibitor used to inhibit matrix metallo-proteinases (MMP) such as type 1 collagenase in studies on would healing and tissue remodeling.
Doxycycline hyclate inhibits the inflammatory response to the Lyme Disease Spirochete Borrelia burgdorferi3. It is a broad spectrum inhibitor of matrix metalloproteinases in vivo.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
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