物质信息
ID:180620
名称和标识
IUPAC标准名
2-methyl-1,4-dihydronaphthalene-1,4-dione
IUPAC传统名
menadione
别名
甲萘醌2-甲基-1,4-萘醌维生素 K3Menadione
化合物性质
安全信息
RTECS编号
QL9100000
GHS警示词
Warning
个人保护装置
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
安全公开号
26-36
GHS警示性声明
P261-P305+P351+P338
德国WGK号
3
GHS危险声明
H302-H315-H319-H335
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
欧盟危险性物质标志
有害性 (Xn)危险公开号
22-36/37/38
理化性质
外观
yellow crystalline
溶解度
oil: soluble
熔点
105-107 °C(lit.)
药理学性质
相关基因信息
human ... NQO1(1728)
描述信息
包装
25, 100 g in glass bottle
Biochem/physiol Actions
Menadione (Vitamin K3) is a synthetic analogue of of 1,4-naphthoquinone with a methyl group in the 2-position. Menadione is used as a phosphatase inhibitor and an inhibitor of mitochondrial DNA polymerase γ (pol γ). Menadione can be used as an oxidative injury (free radical generator) inducing agent.
25, 100 g in glass bottle
Biochem/physiol Actions
Menadione (Vitamin K3) is a synthetic analogue of of 1,4-naphthoquinone with a methyl group in the 2-position. Menadione is used as a phosphatase inhibitor and an inhibitor of mitochondrial DNA polymerase γ (pol γ). Menadione can be used as an oxidative injury (free radical generator) inducing agent.
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参考文献
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