物质信息
ID:180455
名称和标识
别名
[Ala92]-Peptide 6[Ala92]-p16 fragment 84-103
IUPAC标准名
(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]propanamido]propanamido]-5-carbamimidamidopentanamido]-4-carboxybutanamido]acetamido}-3-phenylpropanamido]-4-methylpentanamido]propanamido]-3-hydroxybutanamido]-4-methylpentanamido]-3-methylbutanamido]-3-methylbutanamido]-4-methylpentanamido]-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanamido]propanamido]acetamido}propanamido]-5-carbamimidamidopentanoic acid
IUPAC传统名
(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]propanamido]propanamido]-5-carbamimidamidopentanamido]-4-carboxybutanamido]acetamido}-3-phenylpropanamido]-4-methylpentanamido]propanamido]-3-hydroxybutanamido]-4-methylpentanamido]-3-methylbutanamido]-3-methylbutanamido]-4-methylpentanamido]-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanamido]propanamido]acetamido}propanamido]-5-carbamimidamidopentanoic acid
化合物性质
安全信息
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
德国WGK号
3
保存温度
-20°C
药理学性质
相关基因信息
human ... CDKN2A(1029)
描述信息
Amino Acid Sequence
Asp-Ala-Ala-Arg-Glu-Gly-Phe-Leu-Ala-Thr-Leu-Val-Val-Leu-His-Arg-Ala-Gly-Ala-Arg
Biochem/physiol Actions
Modified fragment from the third ankyrin-like repeat of p16 that binds to cdk4 and cdk6 and inhibits phosphorylation of the retinoblastoma gene product pRb mediated by cdk4-cyclin D.
Asp-Ala-Ala-Arg-Glu-Gly-Phe-Leu-Ala-Thr-Leu-Val-Val-Leu-His-Arg-Ala-Gly-Ala-Arg
Biochem/physiol Actions
Modified fragment from the third ankyrin-like repeat of p16 that binds to cdk4 and cdk6 and inhibits phosphorylation of the retinoblastoma gene product pRb mediated by cdk4-cyclin D.
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参考文献
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