物质信息
ID:178258
名称和标识
IUPAC标准名
(6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
IUPAC传统名
capsaicin
别名
辣椒碱Capsaicin8-甲基-N-香草基-反-6-壬烯酰胺
化合物性质
安全信息
GHS警示词
Danger
GHS危险声明
H301-H315-H317-H318-H334-H335
RTECS编号
RA8530000
联合国危险货物等级
6.1
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别1,2,3
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
腐蚀金属，类别1
腐蚀皮肤，类别1A，1B，1C
严重眼损伤，类别1
RID/ADR
UN 2811 6.1/PG 2
GHS警示性声明
P261-P280-P301+P310-P305+P351+P338-P342+P311
保存温度
2-8°C
联合国危险货物编号
2811
危险公开号
25-37/38-41-42/43
联合国危险货物包装类别(PG)
2
德国WGK号
3
欧盟危险性物质标志
有毒 (T)个人保护装置
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
安全公开号
22-26-28-36/39-45
理化性质
闪点
235.4 °F
113 °C
熔点
62-65 °C(lit.)
产品相关信息
纯度
~60%
描述信息
Quality
Contains approx. 30% dihydrocapsaicin, balance other naturally occurring capsaicinoids.
Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.
Contains approx. 30% dihydrocapsaicin, balance other naturally occurring capsaicinoids.
Biochem/physiol Actions
Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.
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