物质信息
ID:177785
名称和标识
IUPAC传统名
kanamycin; sulfuric acid
IUPAC标准名
(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}oxane-3,4,5-triol; sulfuric acid
别名
卡那霉素 A卡那霉素碱 硫酸盐Kanamycin sulfate from Streptomyces kanamyceticus卡那霉素 硫酸酯 来源于卡那霉素链霉菌
化合物性质
安全信息
GHS警示性声明
P201-P308+P313
GHS警示词
Danger
GHS危险声明
H360
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
危险公开号
61
RTECS编号
NZ3225030
GHS危险品标识
呼吸道过敏，类别1
生殖细胞突变，类别1A，1B，2
致癌性，类别1A，1B，2
生殖毒性，类别1A，1B，2
特定目标器官毒性 – 一次接触，类别1,2
特定目标器官毒性 – 反复接触，类别1,2
吸入危险，类别1
欧盟危险性物质标志
有毒 (T)安全公开号
53-45
德国WGK号
2
理化性质
外观
powder
溶解度
H2O: soluble10-50 mg/mL (As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 5 days.)
产品相关信息
药效
≥750 μg per mg
适用性
meets USP testing specifications
产品质量级别
PREMIUM
描述信息
Application
Used in biotechnology applications to inhibit protein synthesis. Used as a selection agent for cells transformed with kanamycin B (neoR, kanR) resistance gene.
Biochem/physiol Actions
Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria, and mycoplasma.
Used in biotechnology applications to inhibit protein synthesis. Used as a selection agent for cells transformed with kanamycin B (neoR, kanR) resistance gene.
Biochem/physiol Actions
Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria, and mycoplasma.
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