物质信息
ID:177445
名称和标识
IUPAC标准名
1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
IUPAC传统名
norfloxacin
别名
诺氟沙星1-乙基-6-氟-1,4-二氢-4-氧代-7-(1-哌嗪基)-3-喹啉羧酸1-乙基-6-氟-1,4-二氢-4-氧代-7-哌嗪-3-喹啉羧酸Norfloxacin
化合物性质
安全信息
RTECS编号
VB2005000
德国WGK号
2
个人保护装置
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
保存温度
2-8°C
药理学性质
相关基因信息
human ... CYP1A2(1544)rat ... Gabra1(29705)
产品相关信息
适用性
suitable for 1694 per US EPA
纯度
≥98% (TLC)
描述信息
Biochem/physiol Actions
Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase).Mode of action: inhibits bacterial DNA replicationAntimicrobial spectrum: Gram-negative bacteria; less effective against Gram-positive bacteria
Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase).Mode of action: inhibits bacterial DNA replicationAntimicrobial spectrum: Gram-negative bacteria; less effective against Gram-positive bacteria
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