物质信息
ID:130929
名称和标识
别名
MeOSuc-Ala-Ala-Pro-Val-paranitroanilideMeOSuc-Ala-Ala-Pro-Val-PNAMeOSuc-AAPV-PNA
IUPAC标准名
methyl 3-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-2-methyl-1-[(4-nitrophenyl)carbamoyl]propyl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}ethyl]carbamoyl}propanoate
IUPAC传统名
methyl 3-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-2-methyl-1-[(4-nitrophenyl)carbamoyl]propyl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}ethyl]carbamoyl}propanoate
数据登录号
CAS号
描述信息
A specific chromogenic substrate for human neutrophil elastase (Kcat/Km = 120,000 vs. 2700 for pancreatic elastase). Cleavage can be monitored at ~410 nm. Sold on the basis of substrate content.
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参考文献
• Barrett, A.J., et al. 1989. Biochim. J. 260, 259.
• Thornberry, N.A. et al., J. Biol. Chem., 272:17907 (1997).
• Thornberry, N.A. et al., Science, 281:1312 (1998).
• Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.