物质信息
ID:130880
名称和标识
IUPAC标准名
benzyl N-[(1S)-4-carbamimidamido-1-[({[(1S)-1-{[(2S)-1-[(2S)-2-[(4-methoxynaphthalen-2-yl)carbamoyl]pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]carbamoyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]butyl]carbamate
别名
Z-Arg-Gly-Phe-Phe-Pro-MNAZ-Arg-Gly-Phe-Phe-Pro-4-Methoxy-2-NaphthylamineZ-RGFFP-MNA
IUPAC传统名
benzyl N-[(1S)-4-carbamimidamido-1-[({[(1S)-1-{[(2S)-1-[(2S)-2-[(4-methoxynaphthalen-2-yl)carbamoyl]pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]carbamoyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]butyl]carbamate
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描述信息
A fluorogenic/colorimetric substrate for Cathespin D. Suitable for either colorimetric or fluorometric assay. Cathepsin D hydrolyzes the Phe-Phe bond. Requires dipeptidyl aminopeptidase II to free 4-methoxy-b-naphthylamine (MNA).
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参考文献
• Gulmik,S. et al., Mol. Bio., 277:265
• Lojda, Z., et al., Biochem., Biophys. Res. Comm., 148:335 (1987)