物质信息
ID:1240
名称和标识
IUPAC标准名
6-methoxy-N-{[1-(prop-2-en-1-yl)pyrrolidin-2-yl]methyl}-2H-1,2,3-benzotriazole-5-carboxamide
商标名
LiticumLimican
别名
Alizapridum [inn-latin]Alizaprida [inn-spanish]Alizapride
IUPAC传统名
alizapride
化合物性质
理化性质
疏水性(logP)
1.79 [MANNHOLD,R ET AL. (1990)]
描述信息
Drug Groups
approved
Description
Alizapride is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.
Indication
Alizapride is used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.
Pharmacology
Alizapride is a dopamine antagonist.
Half Life
3 hours
Elimination
renal
References
•
Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M: Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial. Cancer Chemother Pharmacol. 1988;22(4):316-20.
[Pubmed]
External Links
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参考文献
• Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M: Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial. Cancer Chemother Pharmacol. 1988;22(4):316-20. Pubmed