Drug Groups

approved

Description

A derivative of 7-aminocephalosporanic acid.

Indication

Cefacetrile is a broad-spectrum first generation cephalosporin antibiotic effective in Gram-positive and Gram-negative bacterial infections.

Pharmacology

Cefacetrile is effective against many Gram-positive bacterial strains and somewhat less effective against Gram-negative species. It works by inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.

Affected Organisms

Half Life

1.2 hours

Protein Binding

23 to 38%

Distribution

Vd of 0.2 to 0.5L/.kg

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