物质信息
ID:1162
名称和标识
别名
Josamicina [inn-spanish]Josamycine [inn-french]Leucomycin V, 3-acetate 4(sup beta)-(3-methylbutanoate)JosamycinJosamycinum [inn-latin]Leucomycin V, 3-acetate 4B-(3-methylbutanoate)JMAntibiotic yl-704 A3Leucomycin V, 3-acetate 4(sup B)-(3-methylbutanoate)Leucomycin A3
IUPAC传统名
josamycin
商标名
Turimycin A5Kitasamycin A3Josacine
IUPAC标准名
(2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4-(acetyloxy)-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-4-hydroxy-2,4-dimethyloxan-3-yl 3-methylbutanoate
化合物性质
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描述信息
Drug Groups
approved
Description
A macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens. [PubChem]
Indication
For the treatment of bacterial infections.
Pharmacology
Josamycin is a macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
Affected Organisms
Enteric bacteria and other eubacteria
References
•
Przybylski P, Pyta K, Stefanska J, Brzezinski B, Bartl F: Structure elucidation, complete NMR assignment and PM5 theoretical studies of new hydroxy-aminoalkyl-alpha,beta-unsaturated derivatives of the macrolide antibiotic josamycin. Magn Reson Chem. 2010 Apr;48(4):286-96.
[Pubmed]
External Links
分子图谱
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参考文献
• Przybylski P, Pyta K, Stefanska J, Brzezinski B, Bartl F: Structure elucidation, complete NMR assignment and PM5 theoretical studies of new hydroxy-aminoalkyl-alpha,beta-unsaturated derivatives of the macrolide antibiotic josamycin. Magn Reson Chem. 2010 Apr;48(4):286-96. Pubmed