物质信息

ID:1027

名称和标识
商标名
Candicidin ACandicidin DVanobidFR-008-III
IUPAC传统名
candicidin
IUPAC标准名
(19Z,21Z,23Z,25Z,27Z,29Z,31Z)-33-{[(3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-17-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-1,3,5,7,37-pentahydroxy-18-methyl-9,13,15-trioxo-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
别名
Candicidin
数据登录号
PubChem SID
CAS号
PubChem CID
化合物性质
理化性质
疏水性(logP)
1.7
描述信息
Drug Groups
approved
Description
Candicidin is an antibiotic obtained from a streptomyces (Streptomyces griseus) and active against some fungi of the genus Candida (C. albicans). Candicidin is administered intravaginally in the treatment of vulvovaginal candidiasis.
Indication
Used in the topical treatment of vulvovaginal candidiasis.
Pharmacology
Candicidin is a polyene antifungal antibiotic produced by a strain of Streptomyces griseus. It is especially effective against Candida albicans (more effective than amphotericin B), and is administered intravaginally in the treatment of vulvovaginal candidiasis.
Affected Organisms
Various Fungus Species
External Links
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