A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties. [PubChem]
Indication
For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive).
Pharmacology
Gentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease. It is thought to work by binding to the DNA of target organisms and causing disruption, mutation or inhibition of DNA replication.
Toxicity
LD50=420 mg/kg (rat, oral). Oral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
Research Area: Infection Biological Activity: Crystal violet is a triarylmethane dye. The dye is used as a histological stain and in Gram’s method of classifying bacteria. Crystal violet has antibacterial, antifungal and anthelmintic properties,which was formerly important as a topical antiseptic. [1]
Application Gentian Violet is the primary stain used in the Gram stain technique for differentiation of Gram-negative versus Gram-postive bacteria. Used as a component of CV cytotoxicity assays.
Application Crystal Violet is the primary stain used in the Gram stain technique for differentiation of Gram-negative versus Gram-postive bacteria. Used as a component of CV cytotoxicity assays.
Application Used as the active component, primary stain, of Gram stain for differentiation of Gram-negative versus Gram-postive bacteria. 包装 25, 100 g in glass bottle Suitability Certified for use with the Gram stain for bacteria, Flemming triple stain with iodine for chromosomes, Lieb′s amyloid stain and Newton′s crystal violet-iodine technique for chromatin and nucleoli.
Frequently Asked Questions Live Chat and Frequently Asked Questions are available for this Product. Components HT901 is composed of certified crystal violet, 2.3%, ammonium oxalate, 0.1%, and 20% ethyl alcohol, SD3A. Application Kit component of Gram Stain kits HT90A and HT90T (for staining of heat-fixed films and tissue, respectively).
Components Contains 2.3% certified crystal violet, 0.1% ammonium oxalate and 20% ethyl alcohol, SD3A. Application Intended for use in the Gram Stain Procedure No. HT90.
An organic chloride salt that is the monochloride salt of crystal violet cation. It has been used in creams for the topical treatment of bacterial and fungal infections, being effective against some Gram-positive bacteria (notably Staphylococcus species) and some pathogenic fungi (including Candida species) but use declined following reports of animal carcinogenicity. It has also been used for dying wood, silk, and paper, as well as a histological stain.
参考文献
PubChem文献
数据源提供
• http://en.wikipedia.org/wiki/Crystal_violet
• Docampo, R., et al.: Drug Metab. Rev., 22, 161 (1972)
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
有害性 (Xn)
环境危害性 (N)
有毒 (T)
腐蚀性 (C)
