CAS 3239-45-0|CAS 3616-78-2|CAS 404-82-0|CAS 113775-47-6|(+)-N-Ethyl-α-methyl-m-[trifluoromethyl]phenethylamine hydrochloride|dexfenfluramine hydrochloride|Dexfenfluramine hydrochloride|ethyl[(2S)-...

基本信息

化学结构

分子式

C₁₂H₁₇ClF₃N

分子量

267.7182896

精确质量

267.10016189

电荷

InChI

InChI=1S/C12H16F3N.ClH/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15;/h4-6,8-9,16H,3,7H2,1-2H3;1H/t9-;/m0./s1

InChIKey

ZXKXJHAOUFHNAS-FVGYRXGTSA-N

Canonic Smiles

CCN[C@H](Cc1cccc(c1)C(F)(F)F)C.Cl

Isomeric Smiles

CCN[C@@H](C)Cc1cccc(c1)C(F)(F)F.Cl

计算属性

JChem

质子受体

质子供体

LogD (pH = 5.5)

0.24381867

LogD (pH = 7.4)

0.7935381

Log P

3.4714873

摩尔折射率

59.2021

极化性

21.97514

极化表面积

12.03

可自由旋转的化学键

里宾斯基五规则

true

数据来源

产品目录

学术数据

数据来源

名称和标识

别名

(+)-N-Ethyl-α-methyl-m-[trifluoromethyl]phenethylamine hydrochlorideDexfenfluramine hydrochloride(+)-Fenfluramine hydrochloride(S)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazoleIsomeride5-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole(αS)-N-Ethyl-α-methyl-3-(trifluoromethyl)benzeneethanamine Hydrochloride(S)-(+)-Fenfluramine Hydrochloridel-Fenfluramine HydrochlorideAdipominS5614 HClGlypolix(αR)-N-Ethyl-α-methyl-3-(trifluoromethyl)benzeneethanamine Hydrochloride(+)-N-Ethyl-α-methyl-m-(trifluoromethyl)phenethylamine HydrochlorideAdifax(+)-Fenfluramine HydrochlorideAcinoPondiminObedrex(S)-Medetomidine(+)-MedetomidinePonderalN-Ethyl-α-methyl-m-(trifluoromethyl)phenethylamine HydrochlorideMPV 1440DexmedetomidineRotondinPesosN-Ethyl-α-methyl-3-(trifluoromethyl)benzeneethanamine Hydrochloriderac Fenfluramine Hydrochlorided-Medetomidine(-)-Fenfluramine Hydrochloride(R)-(-)-Fenfluramine Hydrochloride(-)-N-Ethyl-α-methyl-m-(trifluoromethyl)phenethylamine Hydrochloride

IUPAC传统名

dexfenfluramine hydrochloride

IUPAC标准名

ethyl[(2S)-1-[3-(trifluoromethyl)phenyl]propan-2-yl]amine hydrochloride

名称和标识

数据登录号

MDL号

MFCD00069276

CAS号

3239-45-03616-78-2404-82-0113775-47-6

EC号

221-806-0

PubChem SID

24894746162225794

PubChem CID

66264

数据登录号

化合物性质

产品相关信息

质检报告

下载链接

化合物性质

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描述信息

Sigma Aldrich

F112

Other Notes
Active isomer
Biochem/physiol Actions
(+)-Fenfluramine is a serotonin uptake inhibitor; anoxexic. (+)-Fenfluramine is neurotoxic on prolonged administration or at high dosage. (+)-Fenfluramine releases serotonin from axon terminals by a nonexocytotic mechanism.

TRC

D299000

α2-Adrenergic agonist; (+)-isomer of Medetomidine; sedative; analgesic.

F247596

Anorexic.

F247600

Anorexic.

F247595

Anorexic.

描述信息

参考文献

PubChem文献