化合物信息

05217548 

MP Biomedicals Rare Chemical collection

P1525 

包装
1 g in glass bottle
250 mg in glass bottle

P4394 

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
强效的铂基抗肿瘤剂。与 DNA 二核苷酸 d(pGpG) 形成细胞毒性加合物，诱导链内交联。
Potent chemoimmunotherapeutic drug; stimulates the immune responses by activating macrophages and other cells of the immune system. Cisplatin-treated macrophages show increased antigen presentation function in vitro. Treatment increased cellular NF-κB content and translocation in macrophages. Cisplatin effects are regulated by kinases, phosphatases, and Ca2+/calmodulin. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand crosslinks.
包装
1 g in glass bottle
25, 100, 250 mg in glass bottle

479306 

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
用于防止睾丸癌发展的高活性化学治疗药物。
Biochem/physiol Actions
强效的铂基抗肿瘤剂。与 DNA 二核苷酸 d(pGpG) 形成细胞毒性加合物，诱导链内交联。
包装
1, 5 g in glass bottle

33422 

Biochem/physiol Actions
强效的铂基抗肿瘤剂。与 DNA 二核苷酸 d(pGpG) 形成细胞毒性加合物，诱导链内交联。
Other Notes
Antitumor compound1; Review (chemistry and properties)2,3