化合物信息

Ebselen 

E3520 

Biochem/physiol Actions
An organo-selenium compound possessing antioxidant properties. Inhibits mammalian lipoxygenases in the absence of thiol groups, and glutathione S-transferase and papain via the interaction with cysteine residues. Also inhibits indoleamine 2,3-dioxygenase by covalently modifying a cysteine residue, the effect being reversible with dithiothreitol.1 Inhibits oxidation of low density lipoproteins (LDL).

02158809 

Purity: >99%
Novel selenium-containing anti-flammatory agent. Inhibits 5-LO, CO, NADPH oxidase, and protein kinase C. Potent antioxidant. Possesses a unique glutathione peroxidase-like activity.
Also shown to be an inhibitor of free radical induced apoptosis and neuroprotective agent.

CHEBI:77543 

A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.