CAS 149-73-5|trimethyl orthoformate|TRIMETHYL ORTHOFORMATE|trimethoxymethane|1,1'1''-[Methylidyne tris(oxyl)]-tris[methanel]|METHYL ORTHOFORMATE|2-Methoxyacetaldehyde dimethyl acetal|Methoxymethylal...

基本信息

化学结构

分子式

C₄H₁₀O₃

分子量

106.1204

精确质量

106.06299418

电荷

InChI

InChI=1S/C4H10O3/c1-5-4(6-2)7-3/h4H,1-3H3

InChIKey

PYOKUURKVVELLB-UHFFFAOYSA-N

Canonic Smiles

COC(OC)OC

Isomeric Smiles

COC(OC)OC

计算属性

JChem

质子受体

质子供体

LogD (pH = 5.5)

0.7434416

LogD (pH = 7.4)

0.7434416

Log P

0.7434416

摩尔折射率

25.3384

极化性

10.241282

极化表面积

27.69

可自由旋转的化学键

里宾斯基五规则

true

数据来源

名称和标识

IUPAC传统名

trimethyl orthoformate

别名

TRIMETHYL ORTHOFORMATE1,1'1''-[Methylidyne tris(oxyl)]-tris[methanel]METHYL ORTHOFORMATE2-Methoxyacetaldehyde dimethyl acetalMethoxymethylalMethyl orthoformate三甲基原甲酸酯三甲氧基甲烷TrimethoxymethaneTrimethyl orthoformateOrthoformic acid trimethyl ester原甲酸三甲酯

IUPAC标准名

trimethoxymethane

名称和标识

数据登录号

EC号

CAS号

PubChem CID

Chemspider ID

维基百科标题

Trimethyl_orthoformate

Beilstein号

969215

MDL号

MFCD00008483

PubChem SID

2485843416209309624846805

默克索引号

146884

数据登录号

化合物性质

分子相关蛋白质

暂无数据

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分子图谱

暂无数据

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描述信息

MP Biomedicals

05211396

MP Biomedicals Rare Chemical collection

02157078

1 ml = approx. 0.97 g

Wikipedia

Trimethyl_orthoformate

Sigma Aldrich

305472

包装
1, 2 L in Sure/Seal™
100 mL in Sure/Seal™

108456

包装
20 L in steel drum
500 mL in glass bottle

描述信息

参考文献

PubChem文献

数据源提供

• Reagent for the acid-catalyzed conversion of ketones to their methyl enol ethers in good yield: Synthesis, 38 (1974). For an example, see: Org. Synth. Coll., 8, 357 (1993).

• Protects the cis-2,3-diol system of ribonucleosides as their methoxymethylene acetals (cyclic orthoformates), readily hydrolyzed by mild acid: Synthesis, 408 (1985).

• For further reactions of alkyl orthoformates, see Triethyl orthoformate, A13587.

• In the presence of HCl, is an alternative to formic acid in the synthesis of benzoxazoles from ortho-amino phenols: Org. Prep. Proced. Int., 22, 613 (1990).

参考文献

生物活性

PubChem BioAssay

生物活性

名称和标识

IUPAC传统名

trimethyl orthoformate

别名

IUPAC标准名

trimethoxymethane

数据登录号

EC号

CAS号

PubChem CID

Chemspider ID

维基百科标题

Trimethyl_orthoformate

Beilstein号

969215

MDL号

MFCD00008483

PubChem SID

2485843416209309624846805

默克索引号

146884

描述信息

MP Biomedicals

05211396

MP Biomedicals Rare Chemical collection

02157078

1 ml = approx. 0.97 g

Wikipedia

Trimethyl_orthoformate

Sigma Aldrich

305472

包装
1, 2 L in Sure/Seal™
100 mL in Sure/Seal™

108456

包装
20 L in steel drum
500 mL in glass bottle

参考文献

PubChem文献

数据源提供

• Reagent for the acid-catalyzed conversion of ketones to their methyl enol ethers in good yield: Synthesis, 38 (1974). For an example, see: Org. Synth. Coll., 8, 357 (1993).

• Protects the cis-2,3-diol system of ribonucleosides as their methoxymethylene acetals (cyclic orthoformates), readily hydrolyzed by mild acid: Synthesis, 408 (1985).

• For further reactions of alkyl orthoformates, see Triethyl orthoformate, A13587.

• In the presence of HCl, is an alternative to formic acid in the synthesis of benzoxazoles from ortho-amino phenols: Org. Prep. Proced. Int., 22, 613 (1990).

生物活性

PubChem BioAssay

化合物性质

化合物信息

ID:104754