CAS 127-19-5|CAS 116057-81-9|N,N-DIMETHYLACETAMIDE, ANHYDROSOLV GRADE|N,N-DIMETHYLACETAMIDE, CERTIFIED GRADE|dimethylacetamide|N,N-dimethylacetamide|N,N-DIMETHYLACETAMIDE, HPLC/SPECTRO GRADE|N,N-DIM...

基本信息

化学结构

分子式

C₄H₉NO

分子量

87.12036

精确质量

87.06841391

电荷

InChI

InChI=1S/C4H9NO/c1-4(6)5(2)3/h1-3H3

InChIKey

FXHOOIRPVKKKFG-UHFFFAOYSA-N

Canonic Smiles

CC(=O)N(C)C

Isomeric Smiles

CN(C)C(=O)C

计算属性

JChem

LogD (pH = 7.4)

-0.58

LogD (pH = 5.5)

-0.58

Log P

-0.58

可自由旋转的化学键

质子供体

质子受体

里宾斯基五规则

true

Acid pKa

-1.63

极化表面积

20.31

极化性

9.62

摩尔折射率

24.26

LOG S

0.44

数据来源

名称和标识

别名

N,N-DIMETHYLACETAMIDE, ANHYDROSOLV GRADEN,N-DIMETHYLACETAMIDE, CERTIFIED GRADEN,N-DIMETHYLACETAMIDE, HPLC/SPECTRO GRADEN,N-DIMETHYLACETAMIDEDimethylacetamideN,N-DimethylacetamideN,N-二甲基乙酰胺N,N-Dimethylacetamide-d9N,N-二甲基乙酰胺-d9DMAN,N-Dimethylacetamide, HPLC GradeN,N-二甲基乙酰胺, HPLC级N,N-dimethylacetamidedimethylacetamide

IUPAC传统名

dimethylacetamide

IUPAC标准名

N,N-dimethylacetamide

名称和标识

数据登录号

EC号

CAS号

Chemspider ID

Beilstein号

医学主题词(MeSH)

PubChem CID

维基百科标题

美国药典/FDA物质标识码

CHEMBL

MDL号

PubChem SID

162090444248742722485043124864224248494772485642624893416248863902486422524856380223736433

默克索引号

SureChEMBL数据库

KEGG ID

MetaboLights数据库

Reaxys Registry

ACToR数据库

NMRShiftDB数据库

PDB数据库

PubMed文献链接

BRENDA数据库

CompTox数据库

CHEBI ID

数据登录号

化合物性质

安全信息

有毒 (T)

化合物性质

分子相关蛋白质

PDB Bank

5HCL

分子相关蛋白质

分子图谱

暂无数据

点击上传数据

描述信息

MP Biomedicals

02150928

Purity: 99+%
1 ml = approx. 0.94 g
Cryoprotective properties

05202370

MP Biomedicals Rare Chemical collection

Wikipedia

Dimethylacetamide

Sigma Aldrich

185884

包装
2, 2.5 L in glass bottle
500, 6×500 mL in glass bottle
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

522414

包装
1, 5 g in ampule

17308

包装
1, 2.5 L in glass bottle

44901

General description
Watch a 6-minute presentation that demonstrates the effective use of our High Purity Solvents for GC Headspace Analysis
Suitability
GC-HS 测试用
Protocols & Applications
The Utility of Headspace Grade Solvents for the Analysis of Organic Volatile Impurities

38838

General description
可以成本价获得专用手册 (85475)。
Other Notes
可能实行销售限制

38839

包装
1 L in Sure/Seal™
250 mL in Sure/Seal™

D137510

包装
1, 2, 2.5, 4 L in glass bottle
20 L in steel drum
500, 6×500 mL in glass bottle
Legal Information
DuPont 产品
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

270555

包装
1, 2, 4×4 L in glass bottle
100 mL in glass bottle
18 L in VerSA-Flow™
法律信息
CHROMASOLV 注册商标 Sigma-Aldrich Laborchemikalien GmbH

154806

包装
1, 2 L in glass bottle

271012

包装
1, 6×1, 2 L in Sure/Seal™
View returnable container options.
100, 12×100 mL in Sure/Seal™
200 L in Pure-Pac™ 1

ChEBI

CHEBI:84254

A member of the class of acetamides that is acetamide in which the hydrogens attached to the N atom have been replaced by two methyl groups respectively. Metabolite observed in cancer metabolism.

描述信息

参考文献

PubChem文献

数据源提供

• Morris, J., et al., Biotechniques, 35: 956-968.

• Useful solvent in halex fluorinations of chloroarenes; compare Sulfolane, A13466.

• Dipolar aprotic solvent, cf N,N-Dimethylformamide, A13547, Dimethyl sulfoxide, A13280, 1-Methyl-2-pyrrolidinone, A12260.

• In the presence of triflic anhydride and 2,4,6-collidine, forms a highly-reactive keteniminium triflate, which undergoes a [2+2] cycloaddition reaction with terminal alkenes to give, after hydrolysis a 3-alkylcyclobutanone: J. Am. Chem. Soc., 107, 2192 (1985); Org. Synth. Coll., 8, 306 (1993):

• Reacts with alkyl and aryl Grignard reagents to give methyl ketones in good yields: Synthesis, 228 (1984).

• See also Sodium hydride, 13431, for warning.

• Undergoes Vilsmeier-type reactions (compare DMF), with reactive substrates, introducing an acetyl group: Chem. Ber., 97, 616 (1964).

参考文献

生物活性

PubChem BioAssay

生物活性

名称和标识

别名

IUPAC传统名

dimethylacetamide

IUPAC标准名

N,N-dimethylacetamide

数据登录号

EC号

CAS号

Chemspider ID

Beilstein号

医学主题词(MeSH)

PubChem CID

维基百科标题

美国药典/FDA物质标识码

CHEMBL

MDL号

PubChem SID

162090444248742722485043124864224248494772485642624893416248863902486422524856380223736433

默克索引号

SureChEMBL数据库

KEGG ID

MetaboLights数据库

Reaxys Registry

ACToR数据库

NMRShiftDB数据库

PDB数据库

PubMed文献链接

BRENDA数据库

CompTox数据库

CHEBI ID

分子相关蛋白质

描述信息

Purity: 99+%
1 ml = approx. 0.94 g
Cryoprotective properties

05202370

MP Biomedicals Rare Chemical collection

Wikipedia

Dimethylacetamide

Sigma Aldrich

185884

包装
2, 2.5 L in glass bottle
500, 6×500 mL in glass bottle
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

522414

包装
1, 5 g in ampule

17308

包装
1, 2.5 L in glass bottle

44901

38838

General description
可以成本价获得专用手册 (85475)。
Other Notes
可能实行销售限制

38839

包装
1 L in Sure/Seal™
250 mL in Sure/Seal™

D137510

包装
1, 2, 2.5, 4 L in glass bottle
20 L in steel drum
500, 6×500 mL in glass bottle
Legal Information
DuPont 产品
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

270555

包装
1, 2, 4×4 L in glass bottle
100 mL in glass bottle
18 L in VerSA-Flow™
法律信息
CHROMASOLV 注册商标 Sigma-Aldrich Laborchemikalien GmbH

154806

包装
1, 2 L in glass bottle

271012

包装
1, 6×1, 2 L in Sure/Seal™
View returnable container options.
100, 12×100 mL in Sure/Seal™
200 L in Pure-Pac™ 1

ChEBI

CHEBI:84254

A member of the class of acetamides that is acetamide in which the hydrogens attached to the N atom have been replaced by two methyl groups respectively. Metabolite observed in cancer metabolism.

参考文献

PubChem文献

数据源提供

• Morris, J., et al., Biotechniques, 35: 956-968.

• Useful solvent in halex fluorinations of chloroarenes; compare Sulfolane, A13466.

• Dipolar aprotic solvent, cf N,N-Dimethylformamide, A13547, Dimethyl sulfoxide, A13280, 1-Methyl-2-pyrrolidinone, A12260.

• Reacts with alkyl and aryl Grignard reagents to give methyl ketones in good yields: Synthesis, 228 (1984).

• See also Sodium hydride, 13431, for warning.

• Undergoes Vilsmeier-type reactions (compare DMF), with reactive substrates, introducing an acetyl group: Chem. Ber., 97, 616 (1964).

生物活性

PubChem BioAssay

化合物性质

安全信息

有毒 (T)

化合物信息

ID:103204