物质信息
ID:813
名称和标识
商标名
Afrin Cherry 12 Hour Nasal SprayAfrin Extra Moisturizing 12 Hour Nasal SprayAfrin Original 12 Hour Nose DropsAfrin Original 12 Hour Pump MistNasal Relief 12 Hour Nasal SprayOxylazineNasivineNavasinNavisinNezerilNostrilla 12 Hour Nasal DecongestantAfrinAfrin Sinus 12 Hour Nasal SprayDristan Long Lasting Mentholated Nasal SprayIliadinAfrin Original 12 Hour Nasal SprayGenasal Nasal Spray Up to 12 Hour ReliefHazolNafrineOcuClearVicks Sinex 12 Hour Ultra Fine Mist for Sinus ReliefDuramist Plus Up To 12 Hour Nasal Decongestant SprayDuration 12 Hour Nasal SprayNeo-Synephrine 12 Hour SprayRhinolitanVicks Sinex 12 Hour Nasal SprayVisine L.RRhinofrenolSinerolVisine L.R.Dristan Long Lasting Nasal MistDrixoral Nasal Solution
别名
oxymetazoline hydrochloride crystallineOxymetozolineOxymetazolineOxymethazolineOximetazolinum
IUPAC标准名
6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
IUPAC传统名
oxymetazoline
化合物性质
理化性质
疏水性(logP)
3.4
描述信息
Drug Groups
approved
Description
A direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1251)
Indication
For treatment of nasal congestion and redness associated with minor irritations of the eye
Pharmacology
Oxymetazoline a adrenergic alpha-agonists, direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion The sympathomimetic action of oxymetazoline constricts the smaller arterioles of the nasal passages, producing a prolonged (up to 12 hours), gentle and decongesting effect. Oxymetazoline elicits relief of conjunctival hyperemia by causing vasoconstriction of superficial conjunctival blood vessels. The drug's action has been demonstrated in acute allergic conjunctivitis and in chemical (chloride) conjunctivitis.
Affected Organisms
Humans and other mammals
External Links
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