物质信息
ID:740828
名称和标识
IUPAC标准名
potassium fluoride
IUPAC传统名
potassium fluoride
别名
Potassium fluoride, anhydrous氟化钾, 无水
化合物性质
理化性质
密度
2.48
熔点
859°C
折射率
1.363
外观
Crystalline
沸点
1505°C
安全信息
GHS危险声明
H301-H311-H331
TSCA收录
是
危险公开号
23/24/25
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别1,2,3
联合国危险货物等级
6.1
联合国危险货物包装类别(PG)
III
RTECS编号
TT0700000
安全公开号
26-45
GHS警示性声明
P261-P301+P310-P361-P302+P352-P405-P501A
联合国危险货物编号
UN1812
欧盟危险性物质标志
有毒 (T)保存注意事项
Hygroscopic
产品相关信息
纯度
99%
描述信息
暂无数据
点击上传数据
分子图谱
暂无数据
点击上传数据
参考文献
• KF can also behave as a base in a wide variety of applications:
• Widely used in "halex" fluorination reactions for the preparation of aryl fluorides from the corresponding chlorides by heating in a dipolar aprotic solvent, e.g. tetramethylene sulfone: J. Fluorine Chem., 46, 529 (1990). Other solvents including DMSO, DMA and NMP are also successfully employed. For a review of the preparation of aryl fluorides by halogen exchange, see: Chem. Ind. (London), 518 (1986). Aryl nitro groups can also be displaced in suitable molecules: J. Org. Chem., 56, 6406 (1991). Relative rates for aromatic fluorodenitration in different solvents were found to be: DMSO > tetramethylene sulfoxide > DMA > NMP > tetramethylene sulfone >> acetonitrile > DME: J. Fluorine Chem., 35, 591 (1987).
• Reviews: Fluoride ion as a base in organic synthesis: Chem. Rev., 80, 429 (1980). Alkali metal fluorides in organic synthesis: Synthesis, 169 (1983). See also Cesium fluoride, 12885.
• For use in trifluoromethylation of aromatic, allylic and ɑ-carboxy halides, see Methyl chlorodifluoroacetate, A18623.
• In the Henry reaction of 1-nitropropane with an aldehyde: Org. Synth. Coll., 9, 242 (1998). For the methylenation of catechols with Dibromomethane, A10456, in DMF: Tetrahedron Lett., 3361 (1976). In an olefination reaction with 2,2,2-Trifluoroacetophenone, A11403: J. Org. Chem., 59, 2898 (1994). In combination with 18-crown-6 for selective removal of Fmoc protecting groups under mild conditions: Synth. Commun., 24, 187 (1994).
• An active form of KF has been prepared by recrystallization from methanol followed by drying at 100oC: Tetrahedron, 51, 6363 (1995).
• Has been used in cleavage of silyl protecting groups under phase-transfer conditions (see tert-Butyldimethylchlorosilane, A13064): J. Am. Chem. Soc., 90, 4462, 4464 (1968); 96, 2250 (1974); J. Chem. Soc., Chem. Commun., 514 (1979).