物质信息
ID:735775
名称和标识
IUPAC传统名
bis(2-oxo-1,3-oxazolidin-3-yl)phosphinoyl chloride
别名
Bis(2-oxo-3-oxazolidinyl)phosphinic chlorideBOP-Cl双(2-氧代'-3-噁唑烷基)次磷酰氯
IUPAC标准名
bis(2-oxo-1,3-oxazolidin-3-yl)phosphinoyl chloride
化合物性质
安全信息
安全公开号
26-36/37/39-45
联合国危险货物编号
UN3261
GHS危险声明
H314-H318
欧盟危险性物质标志
腐蚀性 (C)RTECS编号
SZ5871000
GHS危险品标识
腐蚀金属，类别1
腐蚀皮肤，类别1A，1B，1C
严重眼损伤，类别1
保存注意事项
Moisture Sensitive
联合国危险货物等级
8
TSCA收录
否
GHS警示性声明
P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501A
危险公开号
34
联合国危险货物包装类别(PG)
II
理化性质
熔点
ca 195°C dec.
产品相关信息
纯度
97%
描述信息
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分子图谱
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参考文献
• These are also formed in high yield by cyclization of ?-amino acids: Bull. Korean Chem. Soc., 12, 457 (1991).
• For use in the direct selective 5'-acylation of nucleosides by carboxylic acids, (without 3'-protection), see: Tetrahedron, 44, 229 (1988). For high yield dehydration of carboxylic acids to anhydrides, see: Synthesis, 616 (1981). Also used in macrolide cyclization: J. Am. Chem. Soc., 104, 6818 (1982), and in formation of acyclic esters: Synth. Commun., 14, 515 (1984).
• Coupling reagent for which the rates of reaction with various nucleophiles are sufficiently different to permit a genuine "one-step" coupling of carboxylic acids with amines: Synthesis, 547 (1980). Particularly suitable for coupling N-alkyl amino acids: J. Org. Chem., 51, 3350 (1986). For discussion of strategies for one-step coupling in synthesis of amides, see: Synthesis, 413 (1984), and of the scope and limitations of the reagent in peptide coupling, see: Int. J. Pept. Prot. Res., 29, 574 (1987); J. Org. Chem., 55, 2895 (1990). See also Appendix 6.
• The mixed anhydride formed with carboxylic acids adds to imines to give ?-lactams: Synthesis, 63 (1982):
