物质信息
ID:734093
名称和标识
别名
AzidotrimethylsilaneTrimethylsilyl azide叠氮化三甲基硅烷
IUPAC传统名
trimethylsilyl azide
IUPAC标准名
azidotrimethylsilane
化合物性质
产品相关信息
纯度
94%
理化性质
熔点
-95°C
密度
0.872
闪点
6°C(42°F)
折射率
1.4140
沸点
95-99°C
安全信息
欧盟危险性物质标志
有毒 (T)
易燃性 (F)
环境危害性 (N)GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别1,2,3
对水环境的危害
急性危害，类别1
慢性危害，类别1,2
易燃气体类别1
易燃气溶胶，第1,2类
易燃液体，类别1,2,3
自反应物质和混合物，类型B，C，D，E，F
自燃液体类别1
自燃固体类别1
自我放热物质和混合物，类别1,2
与水接触的物质和混合物，放出易燃气体类别1,2,3
有机过氧化物，类别B，C，D，E，F
联合国危险货物等级
3
GHS危险声明
H225-H300-H310-H330-H400-H410
GHS警示性声明
P210-P301+P310-P303+P361+P353-P304+P340-P320-P330-P361-P405-P501A
危险公开号
11-23/24/25-29-50/53
联合国危险货物编号
UN1992
保存注意事项
Moisture Sensitive
TSCA收录
是
安全公开号
7/8-9-16-23-27-30-33-36/37/39-45-57-60
联合国危险货物包装类别(PG)
II
描述信息
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分子图谱
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参考文献
• Non-explosive hydrazoic acid equivalent in many cycloaddition reactions: e.g. with alkynes to give 1,2,3-triazoles: Chem. Ber., 99, 2512 (1966), nitriles, catalyzed by Di-n-butyltin oxide, L14491, to give tetrazoles: J. Org. Chem., 58, 4139 (1993).
• In combination withSnCl4,?-D-ribofuranosyl acetates are converted to azides: Carbohydr. Res., 232, 359 (1992). Similarly, reaction with tert-halides in the presence of tin(IV) chloride gives tert-azides, which can be converted to iminophosphoranes by Staudinger reduction with Triethyl phosphite, L00339. Hydrolysis completes a one-pot sequence for the conversion of a tert-halide to the corresponding amine: Synthesis, 487 (1987).
• Mitsunobu reaction, in the presence of DIAD, with 1,2- and 1,3-diols leads to regioselective, stereospecific azidation to give predominantly the 2- or 3-azido alcohol with inversion of configuration: J. Org. Chem., 64, 6049 (1999).
• In combination with triflic acid, is useful for the direct amination of aromatics. Aminodiazonium triflate is suggested as the active intermediate. Thus, benzene gives aniline in 95% yield and toluene gives a mixture of o- and p-toluidine: J. Org. Chem., 54, 1203 (1989). See also: Tetrahedron Lett., 32, 4321 (1991).
• For reviews, see: Chem. Soc. Rev., 7, 15 (1978); Synthesis, 861 (1980); Chem. Rev., 88, 351 (1988).
• A mild, convenient synthesis of alkyl azides involves SN2 reaction with the corresponding alkyl halide, phosphate or tosylate, promoted by TBAF: Synthesis, 376 (1995).
• Curtius reaction with acid halides gives isocyanates in one operation: Synth. Commun., 2, 227 (1972): Synthesis, 551 (1972); J. Org. Chem., 38, 2982 (1973). Similarly, pyridine-2,3-dicarboxylic anhydride is converted to 3-azaisatoic anhydride: Synthesis, 972 (1982):
