物质信息
ID:714926
名称和标识
IUPAC标准名
1,4-dimethyl but-2-ynedioate
IUPAC传统名
1,4-dimethyl but-2-ynedioate
别名
Dimethyl acetylenedicarboxylate丁炔二酸二甲酯Butynedioic acid dimethyl esterAcetylenedicarboxylic acid dimethyl ester
化合物性质
理化性质
闪点
86°C(186°F)
熔点
-18°C
折射率
1.4480
沸点
195-198°C
密度
1.156
安全信息
GHS危险品标识
急性毒性（口服，皮肤接触，吸入），类别4
皮肤刺激，类别2
眼刺激，类别2
皮肤过敏，类别1
特定目标器官毒性 -一次接触，类别3
腐蚀金属，类别1
腐蚀皮肤，类别1A，1B，1C
严重眼损伤，类别1
GHS危险声明
H314-H318-H302-H227
GHS警示性声明
P210-P260-P303+P361+P353-P305+P351+P338-P405-P501A
安全公开号
26-36/37/39-45
欧盟危险性物质标志
有害性 (X)
腐蚀性 (C)联合国危险货物等级
8
联合国危险货物编号
UN1760
联合国危险货物包装类别(PG)
II
保存注意事项
Light Sensitive
TSCA收录
是
危险公开号
21/22-34
RTECS编号
ES0175000
产品相关信息
纯度
98%
描述信息
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分子图谱
暂无数据
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参考文献
• Used in synthesis of a wide variety of heterocyclic systems including benzo[b]thiophenes from thiophenols: Acta Chem. Scand.,27, 595 (1973), and chromones from phenols: Austral. J. Chem., 48, 677 (1995):
• Stabilized anions derived from cyclic ?-keto phosphonates undergo ring expansion, via a tandem Michael-Aldol-fragmentation mechanism, to give phosphonates with an additional two carbons in the ring, thus providing a route to highly functionalized medium ring compounds: J. Org. Chem., 60, 3084 (1995):
• For use in the masking of double bonds for subsequent release by cycloreversion, see: J. Org. Chem., 44, 962 (1979). Review of cycloreversion reactions in organic synthesis: Synthesis, 121 (1985).
• Dienophile in Diels-Alder and related reactions. For addition to a bis-allene, followed by dimerization to a paracyclophane, see: Org. Synth. Coll., 7, 485 (1990).
• Reacts with activated carbonyl compounds, such as ɑ-keto esters or ɑ-keto nitriles, in the presence of triphenylphosphine, to give highly functionalized -butyrolactones: J. Org. Chem., 61, 4516 (1996). For a further example with reaction scheme, see 2,2,2-Trifluoroacetophenone, A11403.