物质信息
ID:714104
名称和标识
IUPAC标准名
2-(chloromethyl)pyridine hydrochloride
别名
2-Picolyl chloride hydrochloride2-(Chloromethyl)pyridine hydrochloride2-(氯甲基)吡啶盐酸盐
IUPAC传统名
2-(chloromethyl)pyridine hydrochloride
化合物性质
安全信息
GHS危险品标识
腐蚀金属，类别1
腐蚀皮肤，类别1A，1B，1C
严重眼损伤，类别1
急性毒性（口服，皮肤接触，吸入），类别1,2,3
欧盟危险性物质标志
有害性 (X)
腐蚀性 (C)保存注意事项
Hygroscopic
安全公开号
24-26-36/37/39-45
TSCA收录
否
GHS危险声明
H301-H311-H317-H314-H318
联合国危险货物包装类别(PG)
III
GHS警示性声明
P260-P301+P310-P303+P361+P353-P305+P351+P338-P361-P405-P501A
危险公开号
21/22-34-43
RTECS编号
US6825000
联合国危险货物等级
8
联合国危险货物编号
UN3261
理化性质
熔点
120-124°C
产品相关信息
纯度
98%
描述信息
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分子图谱
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参考文献
• For a study of the base-catalyzed alkylation of p-t-butylcalix[5]arene, see: J. Org. Chem., 61, 2407 (1996).
• The free base, generated from the hydrochloride with aqueous OH-, can be metallated (LDA, -78o) at the methylene group. Subsequent reaction with a ketone provides a route to otherwise inaccessible pyridyloxiranes: Tetrahedron Lett., 35, 3175 (1994). Similarly, reaction of the lithio derivative with an imine gives a pyridylaziridine, generally in good yield: J. Org. Chem., 60, 2279 (1995).
• The free base has also been used for the protection of OH groups as 2-picolyl derivatives, relatively stable to acid (HF, TFA) but selectively cleaved by electrolytic reduction: Acta Chem. Scand. B, B37, 475 (1983); J. Chem. Res. (Synop.), 22 (1977).