物质信息
ID:713728
名称和标识
IUPAC传统名
sodium azide
别名
Sodium azide叠氮化钠
IUPAC标准名
sodium 2λ5-triaz-1-en-2-yn-1-ide
化合物性质
理化性质
熔点
ca 275°C dec
溶解度
Soluble in water and liquid ammonia. Slightly soluble in alcohol
外观
Powder or Granular
密度
1.846
安全信息
GHS危险品标识
对水环境的危害
急性危害，类别1
慢性危害，类别1,2
急性毒性（口服，皮肤接触，吸入），类别1,2,3
GHS警示性声明
P273-P264-P301+P310-P321-P405-P501A
欧盟危险性物质标志
环境危害性 (N)
剧毒 (T+)GHS危险声明
H300-H400-H410
保存注意事项
Air Sensitive
RTECS编号
VY8050000
TSCA收录
是
联合国危险货物等级
6.1
联合国危险货物编号
UN1687
危险公开号
28-32-50/53
安全公开号
28-45-60-61
联合国危险货物包装类别(PG)
II
产品相关信息
纯度
99%
描述信息
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分子图谱
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参考文献
• The reaction of alkyl halides with the highly-nucleophilic azide anion gives alkyl azides which, because of their facile reduction by hydrogenation, SnCl2, P(III) reagents, etc., provide an excellent, mild route to primary amines. For a review of the preparation and synthetic uses of azides, see: Chem. Rev., 88, 297 (1988). The preparation of alkyl azides is ideally suited to phase-transfer methods: Synthesis, 823 (1979); Tetrahedron Lett., 3107 (1978); 30, 1245 (1989). The use of ultrasound has also been found to be effective: Acta Chem. Scand. B, 38, 895 (1984). For a one-pot conversion of alkyl bromides to amines using the Staudinger reaction, see Triethyl phosphite, L00339; see also Triphenylphosphine, L02502. For reviews, see: Tetrahedron, 37, 437 (1981); 48, 1353 (1992).
• Reaction with acyl halides or mixed anhydrides gives acyl azides. These undergo the Curtius rearrangement to isocyanates, which can be isolated, or hydrolyzed in situ to the primary amine. For examples, see: Org. Synth. Coll., 6, 95, 910 (1988).
• For a brief feature on uses of this reagent in Organic synthesis, see: Synlett, 505 (2007).
• Reagent for selective cleavage of methyldiphenylsilyl ethers; see Diphenylmethylchlorosilane, L04162.