物质信息

ID:6577

名称和标识
商标名
AndantonActaprontOdantolNilergexUdantol
IUPAC标准名
dimethyl(1-{9-thia-2,4-diazatricyclo[8.4.0.0^{3,8}]tetradeca-1(10),3,5,7,11,13-hexaen-2-yl}propan-2-yl)amine
别名
IsothipendylIsothipendylum
IUPAC传统名
isothipendyl
数据登录号
CAS号
482-15-5
化合物性质
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描述信息
Drug Groups
approved
Description
Isothipendyl is an antihistamine and anticholinergic used as an antipruritic.
Indication
For the topical treatment of itching associated with allergic reactions.
Pharmacology
Isothipendyl, an azaphenothiazine derivative, competitively binds to histamine (H1) receptors, resulting in inhibition of the pharmacological effects of histamines. It also has some sedative, anticholinergic and antiserotoninergic effects.
Affected Organisms
Humans and other mammals
References
• Moreau A, Dompmartin A, Dubreuil A, Leroy D: Phototoxic and photoprotective effects of topical isothipendyl. Photodermatol Photoimmunol Photomed. 1995 Apr;11(2):50-4. [Pubmed]
External Links
• [Wikipedia]
分子图谱
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参考文献
• Moreau A, Dompmartin A, Dubreuil A, Leroy D: Phototoxic and photoprotective effects of topical isothipendyl. Photodermatol Photoimmunol Photomed. 1995 Apr;11(2):50-4. Pubmed
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