物质信息

ID:553

名称和标识
商标名
PirenzepinTabeBisvanilUlcosanGasterilLeblonPirenzepine GastrozepinGastrozepinPirenzepina [INN-Spanish]Pirenzepinum [INN-Latin]
IUPAC标准名
2-[2-(4-methylpiperazin-1-yl)acetyl]-2,4,9-triazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10-one
别名
Pirenzepine
IUPAC传统名
pirenzepine
数据登录号
PubChem CID
PubChem SID
化合物性质
理化性质
疏水性(logP)
0.6
描述信息
Drug Groups
approved
Description
An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as cimetidine and ranitidine. It is generally well tolerated by patients. [PubChem]
Indication
For the treatment of peptic ulcer, gastric ulcer, and duodenal ulcer.
Pharmacology
Pirenzepine belongs to a group of medications called antispasmodics/anticholinergics. These medications are used to relieve cramps or spasms of the stomach, intestines, and bladder. Pirenzepine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be used to prevent nausea, vomiting, and motion sickness.
Affected Organisms
Humans and other mammals
References
• Czepita D: [Fundamentals of modern treatment of myopia] Ann Acad Med Stetin. 2005;51(2):5-9. [Pubmed]
External Links
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参考文献
• Czepita D: [Fundamentals of modern treatment of myopia] Ann Acad Med Stetin. 2005;51(2):5-9. Pubmed