34.4 mg/mL at 25 oC [YALKOWSKY,SH & DANNENFELSER,RM (1992)]
疏水性(logP)
-1.6
描述信息
Drug Groups
approved; nutraceutical
Description
An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of leucine. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels. [PubChem]
Indication
The branched-chain amino acids may have antihepatic encephalopathy activity in some. They may also have anticatabolic and antitardive dyskinesia activity.
Pharmacology
They provide ingredients for the manufacturing of other essential biochemical components in the body, some of which are utilized for the production of energy, stimulants to the upper brain and helping you to be more alert.
Toxicity
Symptoms of hypoglycemia, increased mortality in ALS patients taking large doses of BCAAs
Affected Organisms
Humans and other mammals
Biotransformation
Hepatic
Absorption
Absorbed from the small intestine by a sodium-dependent active-transport process