物质信息

ID:470

名称和标识
商标名
Cinalukast [Usan:Inn]
IUPAC标准名
3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid
别名
Cinalukast
IUPAC传统名
@cinalukast
数据登录号
PubChem SID
PubChem CID
化合物性质
理化性质
疏水性(logP)
4
描述信息
Drug Groups
approved
Description
Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Indication
For Protection against second- phase inflamation in exercise-induced bronchoconstriction and Asthma.
Pharmacology
Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Affected Organisms
Humans and other mammals
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参考文献
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