物质信息

ID:4545

名称和标识
别名
Ecabetum [inn-latin]12-sulfodehydroabietic acidEcabet [inn]ecabet sodiumEcabet (inn)Ecabet13-Isopropyl-12-sulfopodocarpa-8,11,13-trien-15-oic acidEcabetum
IUPAC传统名
ecabet
商标名
Gastrom
IUPAC标准名
(1R,4aS,10aR)-1,4a-dimethyl-7-(propan-2-yl)-6-sulfo-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid
数据登录号
PubChem CID
PubChem SID
化合物性质
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描述信息
Drug Groups
approved; investigational
Description
Ecabet is a prescription eye drop for the treatment of dry eye syndrome. Ecabet represents a new class of molecules that increases the quantity and quality of mucin produced by conjunctival goblet cells and corneal epithelia. Mucin is a glycoprotein component of tear film that lubricates while retarding moisture loss from tear evaporation. Ecabet is currently marketed in Japan as an oral agent for treatment of gastric ulcers and gastritis.
Indication
For the treatment of reflux oesophagitis and peptic ulcer disease.
External Links
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参考文献
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