物质信息
ID:449807
名称和标识
IUPAC标准名
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
别名
Monacolin KMevacorTancorNergadanMevinacorlovastatinLipofren
IUPAC传统名
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
Inhibitor of cholesterol biosynthesis
Potent inhibitor of HMG-CoA
产品相关信息
生物来源
Metab. of Aspergillus terreus and Monascus ruber
应用领域
Antihyperlipidaemic agent
描述信息
暂无数据
点击上传数据
分子图谱
暂无数据
点击上传数据
参考文献
• Alberts et al (1980) Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent. Proc.Natl.Acad.Sci.USA 77 3957.