物质信息
ID:449776
名称和标识
IUPAC标准名
7H-furo[3,2-g]chromen-7-one
别名
PsoralenFicusinFuro[4',5':6,7]coumarin
IUPAC传统名
7H-furo[3,2-g]chromen-7-one
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
This takes advantage of the high UV absorbance of psoralen
An important use of psoralen is in PUVA treatment for skin problems such as psoriasis and (to a lesser extent) eczema and vitiligo.
生物来源
From Psoralea corylifolia, Ficus salicifolia, Heracleum leskovii, Ruta chalepensis, Dictamnus hispanicus, etc.
Found in common vegetables, e.g. parsnip, celery esp. if diseased or `spoiled'
药理学性质
生物活性机理
Radiosensitizer
描述信息
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分子图谱
暂无数据
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参考文献
• Ceska, O. et al., Experientia, 1986, 42, 1302, (occur, tox)
• Zubia, E. et al., Tetrahedron, 1992, 48, 4239, (synth)
• Murray, R.D.H. et al., The Natural Coumarins, J. Wiley, 1982, (rev)
• Hayakawa, K. et al., J.A.C.S., 1984, 106, 6735, (synth)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, FQD000
• Chatterjee, A. et al., Indian J. Chem., Sect. B, 1977, 15, 212, (synth, uv, pmr)
• Worden, L.R. et al., J.O.C., 1969, 34, 2311, (synth)
• Matsumoto, H. et al., Chem. Pharm. Bull., 1978, 26, 3433, (uv)
• Reisch, J. et al., Chem. Ber., 1979, 112, 1491, (synth)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 173A, (nmr)
• Bergenthal, D. et al., Arch. Pharm. (Weinheim, Ger.), 1978, 311, 1026, (cmr)
• Pardanani, N.H. et al., Aust. J. Chem., 1972, 25, 1537, (synth)
• Austin, D.H. et al., Phytochemistry, 1973, 12, 1657, (biosynth)
• Beier, R.C. et al., Xenobiotics in Foods and Feeds, Amer. Chem. Soc., 1983, 295, (occur)
• Masuda, T. et al., Phytochemistry, 1998, 47, 13-16, (isol, uv, pmr, cmr)
• Chimichi, S. et al., Tetrahedron, 2002, 58, 4859-4863, (synth)