物质信息
ID:449768
名称和标识
IUPAC标准名
4-amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide
别名
SulfadiazineSulfadiazineTriple SulfasTriple SulfoidNeotrizineSulfaloidTerfonylLantrisulTriple SulfaSulfonamides DuplexSulfose
IUPAC传统名
4-amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Used in some countries for control of bacterial disease in farmed fish
Antibacterial agent
药理学性质
生物活性机理
Folate synthesis inhibitor
Restrict folate synthesis through competitive antagonism of PABA
Folate antagonist
描述信息
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分子图谱
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参考文献
• Chang, C.J. et al., J. Med. Chem., 1975, 18, 505, (pmr)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 1477
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 201; 206
• Gehring, T.A. et al., J. Agric. Food Chem., 1996, 44, 3164-3169, (anal)
• Kokila, M.K. et al., Acta Cryst. C, 1995, 51, 333, (cryst struct)
• Bult, A., Pharm. Weekbl., Sci. Ed., 1983, 5, 77, (cmr, tautom)
• Roblin, R.O., J.A.C.S., 1940, 62, 2002, (synth)
• Kracmar, J. et al., Pharmazie, 1975, 30; 447, (uv)
• Joshi, V.V. et al., Indian J. Phys., A, 1983, 57, 79, (cryst struct)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 392A, (nmr)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, MRM250; SNI425; PPP500
• Stober, H. et al., Anal. Profiles Drug Subst., 1982, 11, 523; 1984, 13, 553, (rev, synth, pharmacol, anal)
• Sigel, C.W., Handb. Exp. Pharmacol., 1983, 64, 163, (rev, metab)
• Bass, A.D., Drill's Pharmacol. Med., 4th edn., McGraw-Hill, New York, 1971, 1657, (rev, pharmacol)
• Cai, E., CA, 1982, 96, 57702, (synth)
• Przybylski, M. et al., Adv. Mass Spectrom. Biochem. Med., Proc. Int. Symp. Mass Spectrom. Biochem. Med. 2nd, 3rd, 1976, 1, 309, (ms)