物质信息
ID:449725
名称和标识
别名
AmidoxalThiasinSulfafurazoleSoxomideGantrisinNeoxazolSulfisoxazole
IUPAC标准名
4-amino-N-(dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide
IUPAC传统名
4-amino-N-(dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Protozoacide
Low acute toxicity
Short-acting sulfonamide used for urinary tract infections.
Antiseptic
药理学性质
生物活性机理
Folate antagonist
Restrict folate synthesis through competitive antagonism of PABA
描述信息
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分子图谱
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参考文献
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 207
• Chatterjee, C. et al., Acta Cryst. B, 1982, 38, 1845, (cryst struct)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 1971
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 101A, (nmr)
• Manzo, R.H. et al., J. Pharm. Sci., 1973, 62, 152, (uv)
• IARC Monog., 1980, 24, 275; Suppl. 7, 347; Suppl. 6, 502, (rev, tox)
• Kirk-Othmer Encycl. Chem. Technol., 4th edn., Wiley, 1991, 2, 876, (rev)
• Rudy, B.C. et al., Anal. Profiles Drug Subst., 1973, 2, 487, (rev, synth)
• Bult, A., Pharm. Weekbl., Sci. Ed., 1983, 5, 77, (cmr, tautom)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, SNN500
• Hoeprich, P.D., Antimicrob. Agents Chemother., 1967, 697, (pharmacol)