物质信息
ID:449677
名称和标识
IUPAC标准名
5-amino-2-hydroxybenzoic acid
别名
5-aminosalicylic acidMesalamineAsacolMesalazinePentasaFisalamineClaversalAsalitRowasaSalofalkMesalazine
IUPAC传统名
5-amino-2-hydroxybenzoic acid
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Low acute oral toxicity
Antiseptic
Esters used as sunscreens
Antiinflammatory agent
Drug used for treatment of ulcerative colitis
药理学性质
生物活性机理
Cyclooxygenase inhibitor
Prostaglandin antagonist
描述信息
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分子图谱
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参考文献
• Georgieva, M., Anal. Chim. Acta, 1978, 101, 139
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 1121C, (nmr)
• CRC Atlas of Spectral Data and Physical Constants, b848, (ir, uv)
• Weil, H. et al., Ber., 1922, 55, 2664, (synth)
• Myers, B. et al., Gut, 1987, 28, 196, (metab)
• Dobson, A.J. et al., Acta Cryst. C, 1998, 54, 1632-1634, (cryst struct)
• Lepri, L. et al., J. Chromatogr., 1974, 88, 331
• Dash, A.K. et al., Anal. Profiles Drug Subst., 1998, 25, 209-242, (rev, pharmacol)
• Drain, D.J. et al., J.C.S., 1949, 1498-1503, (N-Ac)
• Hoult, J.R.S., Drugs, 1986, 32, 18, (rev)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 8427
• Prakash, A. et al., Drugs, 1999, 57, 383-408, (rev)
• Clemett, D. et al., Drugs, 2000, 59, 929-956
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 219B, (ir)
• Shavel, J. et al., J. Am. Pharm. Assoc., 1953, 42, 402; CA, 48, 9325
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AMM500