物质信息
ID:449635
名称和标识
别名
KenacortTriamcinoloneVolonAristocortFluoxiprednisoloneLederspan
IUPAC标准名
(1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
IUPAC传统名
(1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
ACTH secretion inhibitor
ACTH antaganist
Glycogen deposition inhibitor
Calcium mobilizer
Glucocorticoid
Gluconeogenesis promoter
Phosphorus mobilizer
Immunosuppressive
产品相关信息
应用领域
Immunosuppressive
Antiinflammatory agent
描述信息
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分子图谱
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参考文献
• Bernstein, S. et al., J.A.C.S., 1956, 78, 5693, (synth)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 586B, (nmr)
• Fried, J. et al., J.A.C.S., 1958, 80, 2338, (synth, pharmacol)
• Florey, K., Anal. Profiles Drug Subst., 1972, 1, 367; 397; 423, (rev)
• Toft, P. et al., Can. J. Pharm. Sci., 1972, 7, 53, (ms)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AQX250; AQY375; AQX500; AQX750
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 739
• Sieh, D.H., Anal. Profiles Drug Subst., 1982, 11, 593; 615; 651, (rev)
• Fiegel, G., Arzneim.-Forsch., 1975, 25, 560, (rev)
• Zbinovsky, V. et al., Anal. Profiles Drug Subst., 1977, 6, 579, (rev)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 6222; 7100; 7152