物质信息
ID:449607
名称和标识
别名
ColchicineColchisolColsaloidColchiceine methyl etherArtrichine
IUPAC标准名
N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.02,7]hexadeca-1(16),2,4,6,11,14-hexaen-10-yl]acetamide
IUPAC传统名
N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.02,7]hexadeca-1(16),2,4,6,11,14-hexaen-10-yl]acetamide
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
Leukocyte migration inhibitor
Interferes with kinin formation
Exact mechanism unknown
Reduces phagocytosis with inflammatory
Phagocytosis inhibitor
Response abatement
产品相关信息
应用领域
Antirheumatic
Immunosuppressive
Cytostatic
Potential HIV inhibitor
生物来源
Chief alkaloid from Colchicum autumnale, many other Colchicum spp., several Merendera spp., Gloriosa superba and others (Liliaceae)
描述信息
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分子图谱
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参考文献
• J.Am.Coll.Cardiol. (26, No. 6, 1549-57, 1995)
• Local delivery of biodegradable microparticles containing colchicine or a colchicine analogue: effects on restenosis and implications for catheter-based drug delivery.