物质信息
ID:449529
名称和标识
IUPAC标准名
1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole
别名
TricolamGlongynBioshikSimplotanFasigyneTinidazole
IUPAC传统名
1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
The free nitro radical generated as a result of this reduction may be responsible for the antiprotozoal activity
The nitro group of tinidazole is reduced by cell extracts of Trichomonas.
产品相关信息
应用领域
Antitrichomonal, antimicrobial agent
Protozoacide
描述信息
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分子图谱
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参考文献
• Caplar, V. et al., J. Het. Chem., 1974, 11, 1055, (synth, bibl)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 528
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 987
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, TGD250
• Carmine, A.A. et al., Drugs, 1982, 24, 85, (rev, pharmacol)
• Chasseaud, L.F. et al., Chem. Comm., 1984, 491, (cryst struct, props)
• Rao, A.K.S.B. et al., J.C.S. Perkin 1, 1989, 1352
• Nord, C.E. et al., J. Antimicrob. Chemother., (Eds.), Suppl. 8, 1982, 10, 1, (numerous papers)
• Nagarajan, K. et al., Indian J. Chem., Sect. B, 1982, 21, 1006, (pmr, uv, ms)
• Reddy, K.C. et al., Indian J. Pharm. Sci., 1982, 44, 6, (synth)