物质信息
ID:449416
名称和标识
IUPAC标准名
5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione
别名
MephobarbitalMebaralProminalPhemitoneMentabalMethylphenobarbitalMethylphenobarbitoneEnfenemalEnphenemalMefobarbital
IUPAC传统名
5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Antispasmodic
Sedative
Analgesic
Anticonvulsant
药理学性质
生物活性机理
Binds brain tissue protein
Produces all levels of CNS mood alteration
Binds plasma-protein
Dose-dependent respiratory depressant
描述信息
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分子图谱
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参考文献
• U.K. Pat., 1929, 339 937; CA, 25, 2738, (synth)
• Craig, C.R. et al., J. Pharmacol. Exp. Ther., 1971, 176, 35, (pharmacol)
• Advovich, H.W. et al., Can. J. Pharm. Sci., 1969, 4, 51, (pmr)
• Saferstein, R. et al., J. Assoc. Off. Anal. Chem., 1973, 56, 1234, (ms)
• Dilli, S. et al., Aust. J. Chem., 1975, 28, 2265, (synth)
• Knabe, J. et al., Arch. Pharm. (Weinheim, Ger.), 1972, 305, 54, (synth)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 2742, (synonyms)
• Murata, M. et al., Chem. Pharm. Bull., 1992, 40, 2605, (synth, R-form)
• Asada, S. et al., Bull. Chem. Soc. Jpn., 1978, 51, 3379, (cmr)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, ENB500
• Siek, T.J. et al., J. Forensic Sci., 1975, 20, 18, (uv)
• Hooper, W.D. et al., Ther. Drug Monit., 1981, 3, 39, (metab)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 301