物质信息
ID:449303
名称和标识
别名
InosineHypoxanthine ribosideInosieOxiamineTrophicardylCarnineHypoxanthosine
IUPAC标准名
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
IUPAC传统名
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Used to treat cardiac disorders
Cardiotonic
生物来源
Prod. by microorganisms, e.g. Bacillus subtilis, E. coli, Saccharomyces cerevisiae, Fusarium spp.
药理学性质
生物活性机理
Activates cellular functions by base pairs with Adenine HFN72-P, Cytosine HDR44-O or Uracil BTP40-U
描述信息
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分子图谱
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参考文献
• Gulland, J.M. et al., J.C.S., 1936, 765, (struct)
• Campoli-Richards, D.M. et al., Drugs, 1986, 32, 383, (rev, Inosine pranobex)
• Chenon, M.T. et al., J.A.C.S., 1975, 97, 4627, (cmr)
• Hawkes, G.E. et al., J.C.S. Perkin 2, 1977, 1268, (N-15 nmr)
• Westhof, E. et al., Z. Naturforsch., C, 1975, 30, 131, (pmr)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, IDE000
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 712B, (ir)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 1551
• Ger. Pat., 1972, 2038262; CA, 76, 99993e, (synth)
• Yamazaki, A. et al., J. Het. Chem., 1978, 15, 353, (rev, synth)
• Kinichi, I. et al., Chem. Pharm. Bull., 1966, 14, 1377, (synth)
• Munns, A.R.I. et al., Acta Cryst. B, 1970, 26, 1114, (cryst struct)
• De Simone, C. et al., Int. J. Immunopharmacol., 1991, 13, 19, (rev, Inosine pranobex)
• Hall, R.H., Biochem. Biophys. Res. Commun., 1963, 13, 394, (isol, deriv)
• Japan. Pat., 1968, 68 13 215; CA, 70, 47808, (synth, isopropylidene)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 215C, (nmr)
• Aviado, D.M., J. Pharmacol., 1983, 14, 47, (rev, pharmacol)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 548; 1379