物质信息
ID:449272
名称和标识
别名
OlzapinZyprexaZolafrenZalastaOlanzapineZyprexa Zydis
IUPAC标准名
5-methyl-8-(4-methylpiperazin-1-yl)-4-thia-2,9-diazatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),5,8,10,12-hexaene
IUPAC传统名
5-methyl-8-(4-methylpiperazin-1-yl)-4-thia-2,9-diazatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),5,8,10,12-hexaene
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Used in the treatment of schizophrenia and bipolar disorder
Antipsychotic agent
药理学性质
生物活性机理
5HT(2) and dopamine D2 receptor antagonist
描述信息
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分子图谱
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参考文献
• Moore, N.A. et al., J. Pharmacol. Exp. Ther., 1992, 262, 545, (pharmacol)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 683
• Eur. Pat., 1991, Lilly, 454 436; CA, 116, 83703u, (synth, pharmacol)
• Fulle, R.W. et al., Res. Commun. Chem. Pathol. Pharmacol., 1992, 77, 87, (pharmacol)
• Fulton, B. et al., Drugs, 1997, 53, 281-298, (rev)
• Bhana, N. et al., Drugs, 2001, 61, 111-161, (rev)