物质信息
ID:449259
名称和标识
IUPAC标准名
5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide
别名
MicronaseGlynaseGlyburideSemi-DaonilGlibenclamideEugluconGilemalDaonilDiaBetaDiabetamideMalixLibanilCalabren
IUPAC传统名
5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Antidiabetic drug (type II diabetes)
Inhibits drug-induced coronary vasodilation
药理学性质
生物活性机理
ATP-sensitive potassium channels (KATP) blocker in pancreatic beta cells
描述信息
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分子图谱
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参考文献
• Prendergast, B.D., Clin. Pharm., 1984, 3, 473, (rev, pharmacol)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 1639B, (nmr)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 6870, (synonyms)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 319
• Katsuda, Y. et al., Circulation, 1995, 92, 511, (pharmacol)
• Aumller, W. et al., Arzneim.-Forsch., 1966, 16, 1640, (synth)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CEH700
• Weber, H. et al., Arzneim.-Forsch., 1969, 19, 1323, (numerous papers)
• Takla, P.G., Anal. Profiles Drug Subst., 1981, 10, 337, (rev)
• Krall, L.P. et al., Clin. Ther., 1984, 6, 746, (rev, pharmacol)
• Am. J. Med., Suppl., 1990, 89, 2A, (rev)