物质信息
ID:449255
名称和标识
IUPAC标准名
cyclopentyl N-[3-({2-methoxy-4-[(2-methylbenzenesulfonyl)carbamoyl]phenyl}methyl)-1-methyl-1H-indol-5-yl]carbamate
别名
ZafirlukastAccolate
IUPAC传统名
cyclopentyl N-[3-({2-methoxy-4-[(2-methylbenzenesulfonyl)carbamoyl]phenyl}methyl)-1-methyl-1H-indol-5-yl]carbamate
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
Potent leukotriene D4 receptor antagonist (LTRA)
产品相关信息
应用领域
Antiasthmatic agent
描述信息
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分子图谱
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参考文献
• Dahlen, S.E. et al., Adv. Prostaglandin, Thromboxane, Leukotriene Res., 1990, 21, 461, (pharmacol)
• Adkins, J.C. et al., Drugs, 1998, 55, 121-144, (pharmacol, rev)
• Matassa, V.G. et al., J. Med. Chem., 1990, 33, 1781, (synth, pharmacol)
• Dunn, C.J. et al., Drugs, 2001, 61, 285-315, (rev)
• Taylor, I.K. et al., Lancet, 1991, 1, 690, (clin trial)
• Eur. Pat., 1986, ICI, 199 543; CA, 106, 176163b, (synth, pharmacol)
• Krell, R.D. et al., Am. Rev. Respir. Dis., 1990, 141, 978, (rev)
• Chung, K.F. et al., Drugs of Today (Barcelona), 1998, 34, 375-388, (rev, pharmacol)