物质信息
ID:449152
名称和标识
别名
GabapentinNeurontinAclonium
IUPAC标准名
2-[1-(aminomethyl)cyclohexyl]acetic acid
IUPAC传统名
2-[1-(aminomethyl)cyclohexyl]acetic acid
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
GABA-like amino acid which penetrates the blood-brain barrier
regulator
Voltage-gated N-type calcium ion channels
产品相关信息
应用领域
Anticonvulsant
CNS depressant
描述信息
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分子图谱
暂无数据
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参考文献
• Ger. Pat., 1976, Goedecke, 2 460 891; CA, 85, 94679h, (synth)
• Vollmer, K.O. et al., Arzneim.-Forsch., 1986, 36, 830, (metab)
• Bartoszyk, G.D. et al., Curr. Probl. Epilepsy, 1986, 4, 147, (rev, pharmacol)
• Pellock, J.M., Drugs of Today (Barcelona), 1998, 34, 31-35, (rev, pharmacol)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 346
• Goa, K.L. et al., Drugs, 1993, 46, 409, (rev)
• Griffiths, G. et al., Helv. Chim. Acta, 1991, 74, 309, (synth, bibl)
• Antiepileptic Drugs, 4th edn., (eds., Levy, R.H. et al), Raven Press, 1995
• Hengy, H. et al., J. Chromatogr., 1985, 341; 473, (hplc)