物质信息
ID:449116
名称和标识
IUPAC标准名
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one
IUPAC传统名
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one
别名
Aripiprazole
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Antipsychotic agent
药理学性质
生物活性机理
Shows presynaptic dopamine autoreceptor agonist activity and postsynaptic dopamine D2-receptor antagonist activity
描述信息
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分子图谱
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参考文献
• Kikuchi, T. et al., J. Pharmacol. Exp. Ther., 1995, 274, 329-336, (pharmacol)
• Inoue, T. et al., Eur. J. Pharmacol., 1997, 321, 105-111, (pharmacol)
• Morita, S. et al., Tetrahedron, 1998, 54, 4811-4818, (metab)
• Yamada, S. et al., J. Pharm. Pharmacol., 1997, 49, 206-208, (pharmacol)
• Eur. Pat., 1990, Otsuka, 367 141; CA, 113, 152468y, (synth, pharmacol)
• Semba, J. et al., Neuropharmacology, 1995, 34, 785-791, (pharmacol)
• Inoue, T. et al., J. Pharmacol. Exp. Ther., 1996, 277, 137-143, (pharmacol)