物质信息
ID:4476
名称和标识
别名
Thenoyltrifluoroacetonealpha-Thenoyltrifluoroacetone1,1,1-Trifluoro-3-(2-thenoyl)acetone.alpha.-Thenoyltrifluoroacetone1-Thenoyl-3,3,3-trifluoroacetoneTTFA2-ThenoyltrifluoroacetonePerfluoroacetyl(2-thenoyl)methane
IUPAC传统名
thenoyltrifluoroacetone
IUPAC标准名
4,4,4-trifluoro-1-(thiophen-2-yl)butane-1,3-dione
化合物性质
理化性质
疏水性(logP)
1.46 [HANSCH,C ET AL. (1995)]
描述信息
Drug Groups
experimental
Description
Thenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration. [PubChem]
Pharmacology
Studies indicate that thenoyltrifluoroacetone is a potent inhibitor of carboxylesterase activity, in addition to its ability to inhibit mitochondrial complex II activity.
Affected Organisms
Humans and other mammals
References
•
Zhang JG, Fariss MW: Thenoyltrifluoroacetone, a potent inhibitor of carboxylesterase activity. Biochem Pharmacol. 2002 Feb 15;63(4):751-4.
[Pubmed]
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参考文献
• Zhang JG, Fariss MW: Thenoyltrifluoroacetone, a potent inhibitor of carboxylesterase activity. Biochem Pharmacol. 2002 Feb 15;63(4):751-4. Pubmed