TFAN reacts with reducing oligosaccharides in the presence of sodium cyanoborohydride to give aminoalditol derivatives, useful for linking to proteins or solid matrices. Treated this way, reducing oligosaccharides were easily separated by HPLC.
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参考文献
• Wong, H., et al.: J. Med. Chem., 17, 785 (1974)
• Kallin, E., et al.: Glycoconjugate Journal, 3, 311 (1986)